Affordable Smartphone-Based Sensor Developed for Parkinson’s Disease Management.
New Delhi:
Scientists have unveiled a new, cost-effective tool to aid in managing Parkinson’s disease. The Institute of Advanced Study in Science and Technology (IASST) has developed an innovative smartphone-based fluorescence sensor that accurately measures L-dopa levels in the body. This breakthrough technology promises to simplify and enhance the management of Parkinson’s disease by allowing precise dosage adjustments of this critical medication.
Parkinson’s disease is characterized by a progressive decline in dopamine-producing neurons, which can be managed with L-dopa, a precursor that converts to dopamine. However, maintaining the correct dosage of L-dopa is crucial—too little can worsen symptoms, while too much can cause severe side effects.
The new sensor, designed by IASST, utilizes a portable, smartphone-based system that integrates a fluorescence turn-on mechanism to detect L-dopa concentrations in biological fluids like blood plasma, sweat, and urine. It employs a silk-fibroin protein nano-layer coated onto reduced graphene oxide nanoparticles to create a highly sensitive and effective detection system.
This device operates with a 365nm LED and a smartphone camera, allowing users to visually monitor color changes corresponding to L-dopa levels. The mobile app processes these changes to provide real-time results, offering a simple and rapid method for monitoring drug levels in remote or resource-limited settings.
With its ability to deliver accurate and timely information, this new sensor is set to significantly improve Parkinson’s disease management, making it easier for patients to receive the optimal dosage and maintain control over their condition.
